Innovations

Be sure with iiSure™ Technology

iiSure is a leap in drug delivery. Only our proprietary sound wave technology directly measures the volume of medication delivered at every dose, helping to ensure accurate delivery and advanced occlusion detection capability.

Repeated verification

iiSure directly measures the volume of medication delivered rather than relying on other measures, like pressure or time.

Systemic reliability

iiSure provides the reliability required to integrate into complex, automated systems.

Designed to support therapy continuity

By alerting users to medication flow issues quickly, iiSure has the potential to support people with conditions that depend on continuous medication delivery.

Meet twiist™—a breakthrough in diabetes management

twiist is the first Automated Insulin Delivery (AID) System built on iiSure sound wave technology. It’s designed from the ground up to give people with diabetes confidence and control over their insulin delivery.

And it's already earning recognition as the winner of the 2026 MedTech Breakthrough Award—Best New Technology Solution for Diabetes Management. Read the press release.

The twiist™ Automated Insulin Delivery (AID) System is for people with type 1 diabetes, 6 years of age and above, available with a prescription, only in the U.S. Visit twiist.com/safety for important safety information.

“MedTech Breakthrough” and the MedTech Breakthrough logo are licensed trademarks of MedTech Breakthrough.

Greater personalized control

The widest glucose target range, from 87 mg/dL (the lowest available) to 180 mg/dL^1-6
Retroactive carb entry
Smallest pump with a 300-unit capacity^1-6
3 bolusing options

Advanced iiSure Technology

May help reduce the risk of unexplained highs by detecting occlusions faster,* so users can take action sooner⁷
Detects occlusions up to 9x faster* than other AID systems

Simplified access

Most patients will pay $0 for the first month and no more than $50 per month after that^†
Delivery through pharmacy channels simplifies prescribing, coverage, and refills

We’re not stopping at type 1 diabetes

The iiSure Technology powering twiist ensures accuracy down to the microdose. While built for diabetes, its precision approach is open to expansion into other categories where dosing and reliability can directly impact outcomes.

A platform for possibility

What we’re providing is bigger than a single product or technology. It's a platform for precision drug delivery.

Wide access

Our business model streamlines access and onboarding with wide and comprehensive pharmacy coverage, to help make our solutions accessible to as many people as possible.

Integrated interoperability

From day 1, we’ve built our platform to scale reliably and responsibly, and our architecture enables seamless collaboration across devices, algorithms, and partners.

Personalized support

Choice and personalization are central to all our tools and support because we believe they can improve outcomes and boost confidence in care.

The twiist™ Automated Insulin Delivery (AID) System is for people with type 1 diabetes, 6 years of age and above, available with a prescription, only in the U.S. Visit twiist.com/safety for important safety information.

*Calculation based on a comparison of the following IFUs. The following reported 1 U/hr basal rate: Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide; Insulet - Omnipod 5 Automated Insulin Delivery System User Guide; Medtronic - MiniMed 780G system User Guide; Beta Bionics - iLet Bionic Pancreas System User Guide. The following reported 2 U/hr basal rate: Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide; Tandem Diabetes Care - Tandem Mobi System User Guide.

^†The twiist™ Savings Program is available to individuals with a valid prescription and commercial insurance that covers twiist. Eligible participants can receive a Starter Kit for $0 and pay no more than $50 for Refill Kits. This offer is not valid for individuals enrolled in Medicare, Medicaid, or any other federal or state programs, or for cash-paying patients and non-covered claims. It is available only in the U.S. and is not valid in Puerto Rico, U.S. Territories, or where prohibited by law. While most commercially insured participants qualify for the $50 Refill Kit offer, those with high-deductible plans who haven't met their deductible may pay more than $50 per Refill Kit until their deductible is met. The maximum benefit is $200 per Refill Kit for covered claims. Terms are subject to change. Call us at 1-877-489-4478 or contact your insurance provider to confirm coverage

References: 1. Sequel Med Tech - twiist Automated Insulin Delivery (AID) System Powered by Tidepool User Guide. 2. Insulet - Omnipod 5 Automated Insulin Delivery System User Guide. 3. Medtronic - MiniMed 780G system User Guide. 4. Beta Bionics - iLet Bionic Pancreas System User Guide. 5. Tandem Diabetes Care - t:slim X2 Insulin Pump User Guide. 6. Tandem Diabetes Care - Tandem Mobi System User Guide. 7. Klonoff DC, et al. Time to Moderate and Severe Hyperglycemia and Ketonemia Following an Insulin Pump Occlusion. J Diabetes Sci Technol. 2024;18(6):1472-1479. 8. Snow K, et al. Early Clinical Performance of the twiist Automated Insulin Delivery System. Poster presented at: The 19th International Conference on Advanced Technologies and Treatments for Diabetes (ATTD 2026); March 11-14, 2026; Barcelona, Spain.

Our innovations